Structure determination of the mammalian ryanodine receptor

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1037754

Funding Status
Closed

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Funded Activity Summary

Heart failure is the leading cause of death worldwide. We will determine the structure of the ryanodine receptor, a calcium channel involved in initiating contraction of cardiac and skeletal muscle. Detailed insights into the function of the ryanodine receptor will result from this work. An atomic structure of the cardiac ryanodine receptor will assist in the development of improved ryanodine receptor inhibitors to prevent and treat congestive heart failure.

Funded Activity Details

Start Date: 2012

End Date: 2017

Funding Scheme: Early Career Fellowships

Funding Amount: $377,397.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

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