Website
http://dataportal.arc.gov.au/NCGP/API/grants/LP170101085
Funding Status
Active
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Funded Activity Summary
Novel chemoenzymatic synthesis and bioconjugation of peptides and proteins. This project aims to solve the critical difficulty of producing the complex peptide insulin and related insulin-like peptides (INSLs) and their analogues. The project will use unique, recyclable enzymes which ligate smaller peptide segments with extraordinary site and substrate selectivity. The expected outcome of the project is novel, cheaper and scalable, enzyme-mediated engineering of this critical class of peptides as biological probes and potential therapeutic agents.Funded Activity Details
Start Date: 06-2019
End Date: 06-2024
Funding Scheme: Linkage Projects
Funding Amount: $619,727.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Proteins and Peptides | Biocatalysis and Enzyme Technology | Medicinal and Biomolecular Chemistry | Medicinal and Biomolecular Chemistry not elsewhere classified
ANZSRC Socio-Economic Objective (SEO)
Human Pharmaceutical Products not elsewhere classified | Human Pharmaceutical Treatments (e.g. Antibiotics) |
