Website
https://dataportal.arc.gov.au/NCGP/API/grants/DP170104792
Funding Status
Closed
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Funded Activity Summary
Evolution of defensive and predatory venom in cone snails. This project aims to determine the molecular and cellular origins and mechanisms regulating venom production and release to establish how defensive venoms evolved in cone snails. Cone snails possess a remarkable ability to rapidly and reversibly switch between separate venoms in response to predatory or defensive stimuli, implying that these are separately evolved and regulated mechanisms. The investigators hypothesise that defensive venoms, originally evolved in the proximal venom duct to protect against threats such as cephalopod and fish predation, have been repurposed in the proximal duct to allow predators to become prey, facilitating the switch from worm to mollusc and fish hunting. The project aims to show the broad implications for the evolution of venoms in animals and discover the regulatory mechanisms driving venom peptide expression.Funded Activity Details
Start Date: 2017
End Date: 12-2020
Funding Scheme: Discovery Projects
Funding Amount: $390,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Animal Cell and Molecular Biology | Genome Structure and Regulation | Evolutionary Biology | Biological Adaptation
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |
