Discovery Projects - Grant ID: DP180100931

Funding Activity

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Funded Activity Summary

Silencing the X chromosome: why and how. The project aims to understand why we have X chromosome inactivation, and examine the fundamental molecular mechanisms of how it is achieved. The project will explore RNA-mediated epigenetic modification of whole chromosomes with innovative molecular methods in placental mammals, and also iconic Australian mammals, to transform our understanding of X chromosome inactivation. Further understanding whole chromosome silencing, will inform future research into potential therapies for chromosomal trisomies.

Funded Activity Details

Start Date: 2018

End Date: 12-2021

Funding Scheme: Discovery Projects

Funding Amount: $432,108.00

Funder: Australian Research Council