Linkage - CSIRO - Grant ID: LC0348524

Funding Activity

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Funded Activity Summary

The Cytochrome P450 Gene Super-family in Drosophila melanogaster; Gene Function and Insecticide Resistance. The cytochrome P450 (Cyp) gene super-family is represented by over 90 sequences in the genome of the vinegar fly, Drosophila melanogaster. To date, four Cyp genes are found to be involved in insecticide resistance. The function of the majority of Cyp genes is unknown. This project will investigate the function and regulation of D. melanogaster Cyp genes, linking the fly's genotype to its phenotype. By studying the effects of Cyp genes on fly survival, Cyp gene expression and regulation, and expressing selected Cyp genes in a yeast expression system, we will enhance our understanding of Cyp gene function and evolution.

Funded Activity Details

Start Date: 10-2003

End Date: 10-2006

Funding Scheme: Linkage - CSIRO

Funding Amount: $193,035.00

Funder: Australian Research Council