Website
http://dataportal.arc.gov.au/NCGP/API/grants/FT130101729
Funding Status
Closed
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Funded Activity Summary
Endocrine signalling from bone cells in the regulation of glucose and energy homeostasis. Osteoporosis, obesity and diabetes are increasingly common, all of which are in urgent need of more effective therapies. This project examines powerful neuropeptide signalling pathways that integrate bone homeostasis with whole body energy and glucose balance. Initial studies have defined the efferent hypothalamic pathways of this system and this project will build upon these findings to examine the feedback signals produced by bone cells to regulate adipose and pancreatic function. Exploring this entirely new paradigm of skeletal biology, will reveal novel circulating factors capable of regulating adipose and glucose economies, as well as bone mass, thereby offering potential therapies for these debilitating conditions.Funded Activity Details
Start Date: 2014
End Date: 12-2017
Funding Scheme: ARC Future Fellowships
Funding Amount: $695,050.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Endocrinology | Metabolic Medicine | Medical Biochemistry and Metabolomics | Cell Neurochemistry
ANZSRC Socio-Economic Objective (SEO)
Diabetes | Preventive Medicine | Skeletal System and Disorders (incl. Arthritis) |
