ARC Future Fellowships - Grant ID: FT130100671

Funding Activity

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Funded Activity Summary

Crosstalk between breast cancer cells and the microenvironment to promote metastasis. Breast cancer spread (metastasis) to distant tissues is usually fatal. It is now clear that cross-talk between cancer cells and other normal cells is essential for metastasis and previous studies have discovered two key mechanisms: tumour cell suppression of immune defence pathways to escape immune recognition, and activation of proteases to promote invasion and blood vessel growth. Using unique models and cellular imaging, this project aims to investigate the cell specific functions of these pathways and the therapeutic potential of altering their expression and function. This project may lead to the development of novel predictors of metastasis in patients and new targeted therapeutics to prevent breast cancer spread.

Funded Activity Details

Start Date: 2014

End Date: 06-2017

Funding Scheme: ARC Future Fellowships

Funding Amount: $754,880.00

Funder: Australian Research Council