Discovery Projects - Grant ID: DP240102772

Funding Activity

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Funded Activity Summary

Viral capsids as high-efficiency nanoreactors. This project aims to develop state-of-the-art single-molecule imaging to visualise DNA synthesis inside authentic retroviral capsids in real time. The project expects to generate new knowledge in the fields of virology, synthetic biology, and nanotechnology by utilising cutting-edge fluorescent labelling reagents and microscopy technology. Expected outcomes include a comprehensive description of retrovirus reverse transcription, development of innovative biophysical techniques for the study of viruses, and an understanding of the engineering principles at play in natural nano-reactors. This project anticipates contributing advanced capabilities in bionanotechnology, benefiting therapeutic, biotechnology and synthetic biology applications.

Funded Activity Details

Start Date: 2024

End Date: 12-2026

Funding Scheme: Discovery Projects

Funding Amount: $618,145.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Biochemistry and cell biology | Reaction kinetics and dynamics | Virology

ANZSRC Socio-Economic Objective (SEO)