Discovery Projects - Grant ID: DP1094176

Funding Activity

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Funded Activity Summary

Cell-free immune reactions and suppression. Insects pests and insect vectors of diseases are managed by toxic substances, but insects have a cunning ability to persist. How pesticide-tolerant insect pests recognise and inactivate chemical and biological toxins is poorly understood. While vertebrates with a closed circulatory system use coagulation reactions mainly for wound-healing, invertebrates employ cell-free aggregation reactions for the sequestration and inactivation of potentially damaging objects and substances. We use insect plasma to dissect recognition and inactivation of damaging objects and substances with the aim to understand tolerance and its inhibition to design novel strategies in delaying tolerance to pesticides in insect pests.

Funded Activity Details

Start Date: 07-2010

End Date: 12-2013

Funding Scheme: Discovery Projects

Funding Amount: $300,000.00

Funder: Australian Research Council