Website
https://dataportal.arc.gov.au/NCGP/API/grants/DP0664311
Funding Status
Closed
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Funded Activity Summary
Innovative Approaches for Defining the Interaction of Insulin like Growth Factor I (IGF I) with the Type 1 IGF Receptor. This study will improve our understanding of the interactions of Insulin-like Growth Factors (IGFs) with their principal receptor, the IGF-1R. A sound understanding of these interactions is essential for the development of non-peptide IGF antagonists designed for therapeutic applications. Such molecules could lead to new therapeutic approaches for diseases in which dysregulation of the IGF system has been implicated including cancer, diabetes and atherosclerosis. Since IGFs are major determinants of growth, the outcomes of this project could also lead to improvements in animal production with major benefit to primary industry. New IGF analogues developed could assist biotechnology exports.Funded Activity Details
Start Date: 2006
End Date: 12-2008
Funding Scheme: Discovery Projects
Funding Amount: $259,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Endocrinology
ANZSRC Socio-Economic Objective (SEO)
Endocrine organs and diseases (incl. diabetes) | Cancer and related disorders | Biological sciences |
