Website
https://dataportal.arc.gov.au/NCGP/API/grants/DP210103079
Funding Status
Active
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Funded Activity Summary
Mechanical modulation of particle-cell interactions. Mechanical forces play critical roles in many biological processes, but how particle mechanical properties modulate particle-cell interactions remains elusive. This project aims to develop new design principles for engineering nano/micromaterials with tunable mechanical properties for improved cell activation and expansion, and to advance knowledge of the role of particle stiffness in modulating receptor-mediated particle-cell interactions. Expected outcomes and benefits include new fundamental understanding of the effect of particle mechanical properties on cell function, new insights into T cell activation and expansion, and new classes of stiffness-tunable fit-for-purpose materials for various applications in cell manufacturing.Funded Activity Details
Start Date: 08-2021
End Date: 07-2024
Funding Scheme: Discovery Projects
Funding Amount: $545,307.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Composite and Hybrid Materials | Functional Materials | Chemical Engineering Design | Materials Engineering
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in Engineering | Expanding Knowledge in Technology |
