Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP160103651
Funding Status
Closed
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Funded Activity Summary
Controlling the first step of differentiation of embryonic cells. This project aims to improve understanding of how diverse cell types are generated for building the body plan of the embryo. The first step of embryonic cell lineage differentiation takes place at early gastrulation when the multipotent embryonic cells acquire the attributes of specific tissue lineages. This project intends to elucidate how inductive signals and gene function are integrated to drive the lineage choice of the naïve cells, by tracking the impact of the activity of signalling pathways and gene regulation on cell differentiation. This may deliver insights into the temporal hierarchy and functional attributes of the molecular switches that control stem cell differentiation. Expected outcomes may have applications in tissue engineering.Funded Activity Details
Start Date: 2016
End Date: 12-2018
Funding Scheme: Discovery Projects
Funding Amount: $594,400.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Developmental Genetics (incl. Sex Determination) | Cell Development, Proliferation and Death | Genetics
