Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP160104106
Funding Status
Closed
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Funded Activity Summary
The design of targetable epigenetic modifiers. The project aims to engineer enzymes as valuable tools for understanding gene expression mechanisms and potentially a technology for altering gene expression in plants, animals or humans in a targetable manner. The genetic information encoded in the DNA of all complex organisms has been shown to be augmented by decorations on both DNA and the histone proteins that package DNA. This so-called epigenetic information is important but not well understood. The project plans to design highly specific and targetable enzymes that can interrogate and manipulate epigenetic information in living cells. Understanding the regulation of gene expression and controlling the expression of chosen genes may form a foundation for applications in agriculture, biology and medicine.Funded Activity Details
Start Date: 2016
End Date: 12-2019
Funding Scheme: Discovery Projects
Funding Amount: $444,800.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Enzymes | Agricultural Molecular Engineering of Nucleic Acids and Proteins | Biochemistry and Cell Biology | Medical Molecular Engineering of Nucleic Acids and Proteins |
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Agricultural and Veterinary Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences
