Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0666572
Funding Status
Closed
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Funded Activity Summary
Identification of functionally important autophosphorylation site(s) on ataxia telangiectasia and Rad 3 - related (ATR) protein kinase. The integrity of our genetic material must be maintained so that it can be passed on from one generation to the next and also to minimize the risk of cancer and other pathologies in an individual. There are multiple proteins involved in protecting our DNA including several enzymes that detect and signal DNA damage to a series of pathways involved in halting the passage of cells through the cell cycle so that repair can occur. This project studies the mechanism of action of one of these enzymes which will be of benefit in designing new compounds to fight disease.Funded Activity Details
Start Date: 2006
End Date: 09-2009
Funding Scheme: Discovery Projects
Funding Amount: $265,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Enzymes | Biochemistry and Cell Biology | Gene Expression | Protein Targeting And Signal Transduction
ANZSRC Socio-Economic Objective (SEO)
Cancer and related disorders | Biological sciences | Inherited diseases (incl. gene therapy) |
