Website
http://dataportal.arc.gov.au/NCGP/API/grants/DE240100295
Funding Status
Active
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Funded Activity Summary
Unlocking the helminth ‘early infection gap’ using 3D cell culture models. This project aims to revolutionise the study of critical early host-parasite interactions using innovative 3D cell culture models, reducing our dependence on animal infections. Liver fluke is the most economically important zoonotic parasite of Australian livestock and is a significant contributor to global food insecurity. Due to the reliance of parasites on mammalian hosts to survive, very little is known about the early infection process. Expected outcomes include new knowledge on key migratory stimuli and liver fluke biology. Benefits include the identification of drug targets and vaccine candidates for use in livestock via the development of animal-free in vitro screening platforms that will serve as a prototype for other parasites.Funded Activity Details
Start Date: 2024
End Date: 12-2026
Funding Scheme: Discovery Early Career Researcher Award
Funding Amount: $455,563.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Host-parasite interactions | Invertebrate biology | Animal protection (incl. pests and pathogens) | Zoology
ANZSRC Socio-Economic Objective (SEO)
