The pharmacokinetic, pharmacodynamic and pharmacogenomic outcomes of reduced dosage of efavirenz: the Encore1 study

Funding Activity

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Funded Activity Summary

Our primary aim is to assess blood concentrations of a drug called efavirenz, an important drug used in the treatment of HIV infection and associate these with variability of genes that control metabolism of the drug. A better understanding of gene variability and how it relates to safety and efficacy outcomes at a reduced, compared to a standard dose of efavirenz could support improved treatment of HIV disease.

Funded Activity Details

Start Date: 2013

End Date: 2015

Funding Scheme: Project Grants

Funding Amount: $1,234,943.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity