Discovery Projects - Grant ID: DP0451527

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0451527

Funding Status
Closed

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Funded Activity Summary

Cytorefractometry - a new technique for refractive index tomography of living cells. An ultrahigh-resolution bifocal optical coherence refractometry is proposed, and will result to micron-scale-resolution refractive index tomography of living cells, termed cytorefractometry. This technique represents an extension from bifocal optical coherence refractometry that has recently shown a remarkable promise for direct, several-frames-per-second, motion-artifact-free determination of refractive index in turbid media, including biological tissue in vivo. We propose to apply our novel technique to study tissue calcification, a serious problem in cardiology, by making use of the refractive index contrast mechanism. Calcification of smooth muscle cells and aorta subdermal implant models will be studied aiming for prevention of calcification-associated pathologies.

Funded Activity Details

Start Date: 2004

End Date: 12-2009

Funding Scheme: Discovery Projects

Funding Amount: $720,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Other Physical Sciences | Optics And Opto-Electronic Physics | Cardiology (Incl. Cardiovascular Diseases) | Biophysics

ANZSRC Socio-Economic Objective (SEO)

Cardiovascular system and diseases | Medical instrumentation |

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