Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP200103463
Funding Status
Closed
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Funded Activity Summary
Control of developmental switches by importin 5. Aims: This project will study a key molecular switch called IPO5, a protein that is required for cells and organs to form and function normally, and it will reveal how it works. Significance: These experiments will provide the first complete description of how this molecular switch controls the behaviour of a cell across its lifespan. IPO5 is highly conserved, so these studies will be relevant to a wide range of animals. Expected Outcomes: This knowledge will reveal how IPO5 controls formation of sperm by revealing what other proteins it binds to and how this affects cell signaling and responses to the environment. Benefits: This will provide information about potential interventions to control fertility or to repair abnormal cells.Funded Activity Details
Start Date: 01-2020
End Date: 01-2023
Funding Scheme: Discovery Projects
Funding Amount: $510,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Animal Developmental and Reproductive Biology | Biochemistry and Cell Biology | Cell Development, Proliferation and Death
