ARC Future Fellowships - Grant ID: FT140100594

Funding Activity

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Funded Activity Summary

Uncovering microRNA decay regulation in mammalian cells. MicroRNAs (miRNAs) constitute a novel mechanism used by cells to regulate gene expression, however, very little is known about the mechanisms affecting miRNA accumulation. Characterisation of the kinetics of miRNA turnover is of paramount importance to establish the reliability of miRNAs as novel biomarkers. This project aims to characterise miRNA stability in mammalian cells, investigate mechanisms of turnover and establish their importance on the regulatory function of miRNAs. Such information is critical in the future development of targeted therapeutics.

Funded Activity Details

Start Date: 2015

End Date: 12-2018

Funding Scheme: ARC Future Fellowships

Funding Amount: $751,454.00

Funder: Australian Research Council