Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP210102342
Funding Status
Active
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Funded Activity Summary
Epigenetic regulation of genomic stability and inheritance. Sperm mediate inheritance by transmitting DNA and associated chemical (epigenetic) modifications to offspring. We hypothesise that epigenetic modifications protect DNA from mutations during sperm formation. Using innovative models, our interdisciplinary team will determine whether loss of specific epigenetic modifications permits mutations in sperm and whether these mutations are transmitted to offspring. Our work will contribute to understanding how new mutations arise in sperm and potentially affect offspring phenotype, adaptation and evolution. As chemicals, drugs and diet can affect epigenetic function, our studies will also contribute to determining how epigenetic inheritance affects environmental, agricultural and healthcare outcomes.Funded Activity Details
Start Date: 09-2021
End Date: 09-2024
Funding Scheme: Discovery Projects
Funding Amount: $517,138.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Epigenetics (incl. Genome Methylation and Epigenomics) | Genome Structure and Regulation | Genetics
