Discovery Projects - Grant ID: DP190100497

Funding Activity

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Funded Activity Summary

Directed evolution of ancestral bacterial flagellar motors. This project aims to produce new knowledge concerning the adaptation of bacterial species to wide environmental changes. The bacterial flagellar motor (BFM) is a motor 40 nanometers in diameter that builds itself into bacterial membranes, rotates five times faster than a Formula One engine, and switches directions in milliseconds. . This project will combine ancestral reconstruction of ancient motor components with protein engineering to understand how the different ion channels that power the BFM in different species are selective for different positive ions. It will inspire and inform future manufacturing in bionanotechnology.

Funded Activity Details

Start Date: 2019

End Date: 07-2022

Funding Scheme: Discovery Projects

Funding Amount: $405,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Phylogeny and Comparative Analysis | Molecular Evolution | Genetics | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |