Website
http://dataportal.arc.gov.au/NCGP/API/grants/LP210200125
Funding Status
Active
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Funded Activity Summary
Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a red blood cell line. Simultaneously, this project aims to generate fundamental insights into mechanisms of human gene regulation. The technological and biological outcomes of this project will be of benefit for future gene editing applications.Funded Activity Details
Start Date: 2023
End Date: 12-2025
Funding Scheme: Linkage Projects
Funding Amount: $412,919.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Gene Expression (incl. Microarray and other genome-wide approaches) | Genome Structure and Regulation | Gene and Molecular Therapy | Genetics
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Technology |
