Website
http://dataportal.arc.gov.au/NCGP/API/grants/DE190101053
Funding Status
Closed
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Funded Activity Summary
Archaeal vesicles: new insights into viral evolution and DNA transfer. This project aims to determine the basis for plasmid and membrane vesicle generation and DNA transfer at the cellular and molecular level. Recent discovery of plasmid vesicles, which transfer plasmid DNA between host cells using viral capsid-like membrane vesicles, suggests they may be an evolutionary precursor for virus particles. The expected project outcomes include the first substantive characterisation of membrane vesicles in the phylum Euryarchaeota, how plasmid vesicles are generated and transmitted, and new insights into how viruses may evolve. This may lead to new avenues for preventing viral transmission and supporting development of new and improved applications biotechnology and the safe delivery of vaccines or genes in animals and humans.Funded Activity Details
Start Date: 2019
End Date: 2019
Funding Scheme: Discovery Early Career Researcher Award
Funding Amount: $421,656.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Microbial Genetics | Virology | Microbiology | Microbiology not elsewhere classified
