Website
http://dataportal.arc.gov.au/NCGP/API/grants/FT180100255
Funding Status
Active
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Funded Activity Summary
Awaking quiescent neural stem cells. This project aims to generate new knowledge in the area of the evolutionary size of animals and plants, which is determined by intrinsic cell regulation and is constrained by nutrient availability. Brain size is perhaps the most profound example of this. Brain size regulation is underpinned by control of proliferation of neural stem cells (NSCs). Using Drosophila NSCs, the project will examine how nutrients impact on NSC quiescence versus activation, a key characteristic of stem cell control throughout evolution. This will increase our understanding of how energy metabolism and nutrition influence organ size control in multicellular organisms, by determining how organs communicate with each other to convert nutrient signals to action stem cell proliferation.Funded Activity Details
Start Date: 2019
End Date: 12-2022
Funding Scheme: ARC Future Fellowships
Funding Amount: $713,125.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Developmental Genetics (incl. Sex Determination) | Biochemistry and Cell Biology | Neurogenetics | Cell Development, Proliferation and Death
ANZSRC Socio-Economic Objective (SEO)
Nervous System and Disorders | Expanding Knowledge in the Biological Sciences |
