Discovery Projects - Grant ID: DP0664267

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0664267

Funding Status
Closed

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Funded Activity Summary

Many Ys in monotremes: multiple sex chromosomes and sex determination in platypus and echidna. Platypus and Echidna are Australian icons, even featuring on our coins. Their unusual biology and ancient relationship to humans make them unique for understanding the mammalian genome, as demonstrated by our recent discovery of ten sex chromosomes in platypus that link mammal and bird sex. Still little is known about their genome, embryo development and how sex is determined. We will identify new genes on all ten sex chromosomes and investigate how they determine sex. The set up of an Australian Monotreme Resource Centre will be crucial for this research and attract worldwide high profile collaborations. We will answer important general questions in monotreme biology and contribute to our understanding of sexual abnormalities in humans.

Funded Activity Details

Start Date: 06-2006

End Date: 05-2011

Funding Scheme: Discovery Projects

Funding Amount: $590,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Meiosis And Recombination | Genome Structure | Genetics | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Reproductive system and disorders | Biological sciences | Inherited diseases (incl. gene therapy) |

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