B cell activation generates antibodies to promote vascular and renal inflammation, remodelling and dysfunction in hypertension

Website
http://purl.org/au-research/grants/nhmrc/1146314

Funding Status
Closed

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Funded Activity Summary

Hypertension is a major contributor to chronic cardiovascular and renal diseases, with recent literature suggesting the pathogenesis is similar to that of autoimmune diseases. This fellowship will enhance the current understanding of the pathogenesis of hypertension and the associated inflammation of the kidneys and vasculature. It will also assess the therapeutic potential of drugs that dampen the immune response in several animal models of hypertension.

Funded Activity Details

Start Date: 2018

End Date: 2022

Funding Scheme: Early Career Fellowships

Funding Amount: $327,193.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Pharmacology and Therapeutics

ANZSRC Socio-Economic Objective (SEO)

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