Discovery Projects - Grant ID: DP170101198

Funding Activity

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Funded Activity Summary

Cellular determinants of retrotransposition. This project aims to understand the processes that control retrotransposition in a genome. Transposable elements make up more than 50% of human genomes. The accumulation of retrotransposons through millions of years of evolution has shaped the genomes of all eukaryotic organisms, including humans. Researchers have elucidated mechanisms the host uses to defend the genome against insertional mutagenesis by retrotransposons, but the cellular machinery and genomic environments needed for retrotransposition are undefined. This project aims to use models to uncover the mechanisms that control retrotransposition. This is expected to reveal more about human origins.

Funded Activity Details

Start Date: 2017

End Date: 12-2018

Funding Scheme: Discovery Projects

Funding Amount: $275,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure and Regulation | Genomics | Molecular Evolution | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |