Discovery Projects - Grant ID: DP240102119

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP240102119

Funding Status
Active

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Funded Activity Summary

How does the chromatin remodeller CHD4 regulate gene expression? The mechanisms that determine how genes are switched on and off in different tissues and at different times are in many ways still mysterious. It is well established that gene expression patterns in complex organisms are determined in part by the manner in which DNA is physically packaged. Our aim is to define new aspects of these mechanisms that revolve around molecular motors that regulate DNA packaging. This foundational knowledge will deepen our understanding of gene regulation in all complex organisms and will inform future efforts to rationally modulate gene expression patterns in agriculture, research and other important areas.

Funded Activity Details

Start Date: 2024

End Date: 12-2027

Funding Scheme: Discovery Projects

Funding Amount: $780,618.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Biochemistry and cell biology | Structural biology (incl. macromolecular modelling) | Genome structure and regulation

ANZSRC Socio-Economic Objective (SEO)

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