Discovery Projects - Grant ID: DP240101869

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP240101869

Funding Status
Active

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Funded Activity Summary

Understanding Mitotic Telomere Deprotection. This project aims to study telomeres, the DNA and protein structures that protect chromosome ends. During cell division, cells under stress intentionally uncap their telomeres. This project expects to generate new knowledge that challenges the conventional notion of telomeres as static elements, showing instead that telomeres can be dynamic signalling hubs. Expected outcomes of this project include an understanding of the genetic, proteomic, and signalling pathways involved in this novel phenomenon. This should provide significant benefits to our fundamental understanding of biological processes that protect human genomes and provide a valuable dataset for research on telomere biology, DNA repair, and genome stability.

Funded Activity Details

Start Date: 2024

End Date: 12-2026

Funding Scheme: Discovery Projects

Funding Amount: $703,903.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell and nuclear division | Cell development proliferation and death | Genetics | Genome structure and regulation

ANZSRC Socio-Economic Objective (SEO)

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