Website
http://dataportal.arc.gov.au/NCGP/API/grants/LE200100190
Funding Status
Closed
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Funded Activity Summary
Electrophysiology Platform for Ion-channel Characterisation. Ion channels are ubiquitous pore-forming membrane proteins, with the human genome encoding >300 ion channels. The diverse roles of ion channels include action potential generation, control of ion flow across secretory and epithelial cells, and regulation of cell volume, motility and proliferation. Pharmacological modulators are powerful tools for probing ion channel function, but for most channels these tools are lacking. Thus, this project aims to develop the first comprehensive toolbox of ion channel modulators using an integrated in vitro/in vivo electrophysiology platform. These pharmacological tools will be made freely available to the Australian research community for probing the mechanism and physiological function of ion channels.Funded Activity Details
Start Date: 08-2020
End Date: 12-2020
Funding Scheme: Linkage Infrastructure, Equipment and Facilities
Funding Amount: $620,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Proteins and Peptides | Characterisation of Biological Macromolecules | Medicinal and Biomolecular Chemistry | Biologically Active Molecules
ANZSRC Socio-Economic Objective (SEO)
Nervous System and Disorders | Expanding Knowledge in the Agricultural and Veterinary Sciences | Expanding Knowledge in the Biological Sciences |
