ARC Future Fellowships - Grant ID: FT170100437

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/FT170100437

Funding Status
Closed

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Funded Activity Summary

Using natural products to inspire discoveries in synthesis and biosynthesis. This project aims to understand the organic chemistry that occurs in the biosynthesis of unusual antibiotic natural products by marine microorganisms. In an interdisciplinary approach, proposed biosynthetic intermediates will be synthesised and screened against newly isolated enzymes from the microorganisms of interest. This will allow the elucidation of biosynthetic pathways, and aid the discovery of new chemoenzymatic reactivity that may be broadly useful in organic synthesis. Non-enzymatic, predisposed organic reactions will also be uncovered during the project. The benefit of this project will be an improvement in our ability to synthesise potential antibiotics using a combined synthetic organic and chemoenzymatic approach. This could lead to useful new antibiotics in the future.

Funded Activity Details

Start Date: 11-2017

End Date: 10-2021

Funding Scheme: ARC Future Fellowships

Funding Amount: $820,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Organic Chemistry | Natural Products Chemistry | Organic Chemical Synthesis

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences |

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