Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP140103513
Funding Status
Closed
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Funded Activity Summary
Comparative toxicology of a fumigant and gasotransmitters: Testing a new model of fumigant toxicity in Caenorhabditis elegans. Fumigants share physical, chemical and functional properties with a medically important class of signalling molecules called gasotransmitters. This project proposes that the toxicity of fumigants is directly caused by their ability to mimic and disrupt gasotransmitter signalling. This project will test this hypothesis using the fumigant phosphine, a chemical that protects the vast majority of the world grain supply from insect pests. This work will show us what makes a fumigant toxic. This knowledge will facilitate the discovery and effective deployment of new fumigants.Funded Activity Details
Start Date: 2014
End Date: 05-2017
Funding Scheme: Discovery Projects
Funding Amount: $355,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Biochemistry and Cell Biology | Genetics not elsewhere classified | Cell Metabolism
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Biological Sciences | Unprocessed Grains |
