Discovery Projects - Grant ID: DP0881850

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0881850

Funding Status
Closed

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Funded Activity Summary

Single Minded 2: Cross coupling or specificity within the bHLH/PAS transcription factor family? Understanding the mechanisms of action of SIM2 may lead to novel ideas towards drug development for diseases such as Down syndrome and cancer. The SIM2 protein can interfere with activity of the related Hypoxia Inducible Factor (HIF), a protein important in stress response and recovery from stroke. Understanding the molecular basis of this interference could aid current strategies being used to manipulate HIF for pharmaceutical benefit.

Funded Activity Details

Start Date: 2008

End Date: 12-2011

Funding Scheme: Discovery Projects

Funding Amount: $330,556.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified | Gene Expression | Genetics | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Cancer and related disorders | Inherited diseases (incl. gene therapy) | Organs, diseases and abnormal conditions not elsewhere classified |

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