Discovery Projects - Grant ID: DP180101890

Funding Activity

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Funded Activity Summary

Adaptation of respiratory chemoreception: role of inhibitory neuropeptides. The project aims to investigate how the retrotrapezoid nucleus (RTN) is involved in respiratory adaptation to hypercapnia. Chemoreceptor neurons in the RTN are crucial for life however, the mechanisms that underlie their basal and stimulated activity, to control breathing, remain to be clarified. This project will investigate the role of galanin in RTN-mediated regulation of breathing. The project looks to determine instructive and multifunctional roles of peptidergic chemosensory neurons and their contribution to local inhibitory control of the respiratory network. New knowledge from the project may in the future assist translational research into respiratory disorders and lead to technological advances.

Funded Activity Details

Start Date: 06-2018

End Date: 12-2023

Funding Scheme: Discovery Projects

Funding Amount: $399,083.00

Funder: Australian Research Council