Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP230103080
Funding Status
Active
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Funded Activity Summary
Extracting energy from air: mechanism of a bacterial hydrogenase. The atmosphere has recently been shown to be a key source of energy for diverse soil bacteria. Bacteria use complex enzymes, namely Huc-type hydrogenases, to harvest atmospheric hydrogen directly from air to support growth and survival. However, little is known about how Huc functions within and outside cells. By synergising expertise in microbiology, biochemistry, and chemistry, we will resolve the mechanism, assembly, and integration of Huc, including the basis of its remarkably high affinity and oxygen insensitivity compared to previously studied hydrogenases. This project will enable biotechnological applications, as the first study of an enzyme that extracts energy from air, and has broad ecological and biogeochemical implications.Funded Activity Details
Start Date: 2023
End Date: 12-2025
Funding Scheme: Discovery Projects
Funding Amount: $694,096.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Microbial genetics | Enzymes | Biochemistry and cell biology
ANZSRC Socio-Economic Objective (SEO)
