Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP160103826
Funding Status
Closed
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Funded Activity Summary
Structure and function of predatory and defensive venoms in cone snails. This project aims to investigate newly-discovered cone snail venoms to accelerate the search for novel bioactive peptides. It was recently discovered that cone snails can rapidly and reversibly switch between distinct venoms in response to predatory or defensive stimuli, implying that defensive and predatory venoms have evolved under separate selection pressures. The project plans to obtain separate predatory and defensive venoms and venom duct tissue from individual cone snails to compare and contrast the structure and function of conotoxins evolved for predation versus those evolved for defence, to elucidate the structure and function of these important classes of bioactive peptides.Funded Activity Details
Start Date: 2016
End Date: 12-2019
Funding Scheme: Discovery Projects
Funding Amount: $469,986.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics) | Proteins and Peptides | Basic Pharmacology | Medicinal and Biomolecular Chemistry |
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences
