Discovery Projects - Grant ID: DP240102642

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP240102642

Funding Status
Active

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Funded Activity Summary

Unravelling Efficient Nucleic Acid Delivery Using Multilayer Nanoparticles. Developing smarter nanoparticles is critical for maximising the potential of biological therapeutics such as nucleic acids. Currently, the efficiency of nanoparticle delivery remains low due to the inability of carriers to migrate different biological regions. The aim of this project is to develop responsive polymer nanoparticles that can more effectively migrate cell barriers by a two-staged release based on the combination of different self-immolative polymers. This project will allow the development of design rules for understanding how nanoparticle structure can be optimised to improve nucleic acid delivery. This work will have important benefits such as developing new nanotechnology industry and skilled graduates for Australia.

Funded Activity Details

Start Date: 2024

End Date: 12-2026

Funding Scheme: Discovery Projects

Funding Amount: $566,242.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Macromolecular materials | Macromolecular and materials chemistry

ANZSRC Socio-Economic Objective (SEO)

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