Linkage Projects - Grant ID: LP160100657

Funding Activity

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Funded Activity Summary

Enhanced sensitivity of electrospray ionization mass spectrometry. Enhanced sensitivity of electrospray ionization mass spectrometry. This project aims to enhance the sensitivity of nano-electrospray ionization mass spectrometry (nanoESI-MS) by an order of magnitude by simultaneously overcoming the two interdependent limitations in ion generation and transmission efficiency. This project will design glass capillaries and tubes with complex structures to enable both multiplexing ion generation from a single capillary and geometrically matching the bore of the tube collecting the emitted ion plume. NanoESI-MS has become an indispensable analytical tool for proteomics and synthetic chemistry. The significant enhancement of nanoESI-MS sensitivity in this project is expected to accelerate progress in disease research, biomarker discovery and drug development.

Funded Activity Details

Start Date: 01-2017

End Date: 06-2021

Funding Scheme: Linkage Projects

Funding Amount: $500,000.00

Funder: Australian Research Council