Discovery Projects - Grant ID: DP170103790

Funding Activity

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Funded Activity Summary

Mechanism and function of dying cell disassembly. This project aims to elucidate the molecular machinery that disassembles dying cells, and the role of this process in cell clearance. Billions of cells in the body die daily as part of normal turnover. Dying cells must be rapidly removed, as their accumulation can interfere with normal tissue functions. To efficiently clear dead cells, dying cells can disassemble into smaller fragments that neighbouring cells engulf. Understanding the mechanistic basis and function of dying cell disassembly is expected to generate knowledge of the downstream consequence of cell death. This breakthrough will be important in many fields of research including cell biology and biochemistry, and generate basic knowledge that can ultimately be applied in medical science to understand or treat pathological conditions associated with cell death.

Funded Activity Details

Start Date: 04-2017

End Date: 04-2020

Funding Scheme: Discovery Projects

Funding Amount: $391,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |