Novel fluorescent probes of cellular microenvironments to study the mechanism of action of endoperoxide antimalarials

Funding Activity

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Funded Activity Summary

Malaria is responsible for the deaths of about two million children each year. As current drugs become increasingly useless due to the development of parasite resistance, there is an urgent need for new antimalarials. Artemisinin, an ancient Chinese drug that is extracted from wormwood, is now a front-line antimalarial, however its mechanism of action is not clear. Information about how artemisinin works is needed to help design cheap synthetic drugs that work in the same way.

Funded Activity Details

Start Date: 2009

End Date: 2014

Funding Scheme: NHMRC Project Grants

Funding Amount: $983,305.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural immunology and immunochemistry

ANZSRC Socio-Economic Objective (SEO)

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