Website
http://dataportal.arc.gov.au/NCGP/API/grants/LP200100537
Funding Status
Active
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Funded Activity Summary
A novel platform for the biosynthesis of commercially valuable saxitoxins. Saxitoxins are potent microbial toxins, which pose a significant threat to food and water quality. Highly pure saxitoxins are required for environmental monitoring and studies of cell physiology. Certain analogues have also shown promise as long-lasting and non-addictive pain blockers. However, the procurement of these compounds from natural sources is convoluted and unsustainable. This project aims to use the latest synthetic biology techniques to characterise, modify and express saxitoxin biosynthesis pathways, thereby providing a sustainable source of toxin analogues of value to industry and research. This novel 'green technology' will benefit the environment, human health and the Australian economy.Funded Activity Details
Start Date: 04-2021
End Date: 12-2024
Funding Scheme: Linkage Projects
Funding Amount: $419,059.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Animal Cell and Molecular Biology | Natural Products Chemistry | Biochemistry and Cell Biology | Synthetic Biology
ANZSRC Socio-Economic Objective (SEO)
Natural Hazards in Fresh, Ground and Surface Water Environments | Human Pharmaceutical Treatments (e.g. Antibiotics) | Environmentally Sustainable Manufacturing not elsewhere classified |
