Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140102495
Funding Status
Closed
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Funded Activity Summary
Brain Regulation of Reproduction: Challenging the ‘KNDy’ Hypothesis. The brain switches reproduction on and off by changing the frequency of pulses of gonadotrophin releasing hormone. The processes that produce the pulses have been a puzzle for decades but, recently, brain cells that produce three peptides (kisspeptin, neurokinin B, dynorphin), known as ‘KNDy cells’, have been heralded as the ‘missing link’, or even the ‘pulse generator’. Using sheep, this project will challenge the KNDy hypothesis with pheromones and with acute increases in nutrition, two factors that rapidly increase the frequency of gonadotrophin releasing hormone pulses. The outcomes of this research are directly relevant to the optimisation of reproductive management in farm animals, wildlife and humans.Funded Activity Details
Start Date: 2014
End Date: 12-2018
Funding Scheme: Discovery Projects
Funding Amount: $390,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Zoology | Endocrinology | Animal Neurobiology | Animal Reproduction
ANZSRC Socio-Economic Objective (SEO)
Reproductive System and Disorders | Expanding Knowledge in the Biological Sciences | Sheep - Meat |
