Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP230103107
Funding Status
Active
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Funded Activity Summary
Synthetic biology tools for just-in-time control of biosynthetic pathways. Synthetic biology enables sustainable synthesis of precious chemicals, ranging from drugs to biomaterials. Using microbes, high production levels are usually attained by overexpressing the genes that make the desired product, but this simple approach often fails for antibiotics and other compounds that are toxic to microbes. Using synthetic biology this project builds genetic circuits enabling smart, just-in-time activation of target genes, which is pervasive in natural pathways. Using these circuits we will boost 1) the production of a valuable antibiotic and 2) calcite precipitation in self-healing concrete. This approach enables the biosynthesis of many other chemicals, leading to cleaner and greener bio-factories.Funded Activity Details
Start Date: 2023
End Date: 12-2025
Funding Scheme: Discovery Projects
Funding Amount: $458,799.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Biochemistry and cell biology | Synthetic biology |
ANZSRC Socio-Economic Objective (SEO)
