ARC Future Fellowships - Grant ID: FT160100063

Funding Activity

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Funded Activity Summary

How cells control autophagy during nutrient starvation and stress. This project aims to understand how human cells form autophagosomes during nutrient starvation and stress conditions, including bacterial invasion and mitochondrial dysfunction. Autophagy is a conserved intracellular degradation pathway which fungi, plants, insects and mammals use to respond to starvation and stress. Autophagy can provide nutrients by recycling cellular components, and protect cells from dysfunctional organelles and invading pathogens by mediating their removal. The autophagosome is a vesicular membrane structure important in autophagy by delivering material destined for degradation to the lysosome. Better understanding how plant and human cells protect themselves during starvation and stress is expected to benefit the environment and economy.

Funded Activity Details

Start Date: 2017

End Date: 12-2020

Funding Scheme: ARC Future Fellowships

Funding Amount: $663,324.00

Funder: Australian Research Council