Discovery Projects - Grant ID: DP220101644

Funding Activity

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Funded Activity Summary

Tuning mesenchymal stem cell lifespan, performance, and differentiation. This project aims to fully characterise a unique molecular process that strongly modulates mesenchymal stem cell lifespan and behaviour. This work is significant, as it is expected to reveal new concepts underpinning the mechanistic actions of classical structural proteins. It will also shape a more nuanced understanding of the context-dependent mechanical and biochemical signals that regulate stem cell fate and function. Expected outcomes include new knowledge surrounding native extracellular matrix and stem cell biology, and the development of strategies to define and tailor stem cell properties. This work is anticipated to drive new technologies that can efficiently and robustly manipulate stem cells for diverse functional applications.

Funded Activity Details

Start Date: 07-2022

End Date: 06-2025

Funding Scheme: Discovery Projects

Funding Amount: $570,000.00

Funder: Australian Research Council