Discovery Projects - Grant ID: DP170104722

Funding Activity

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Funded Activity Summary

Expanding the organometallic toolbox for constructing heterocycles. This project aims to design and synthesise stereospecific cyclic molecules. This is a problem for chemists, particularly when bioactivity and medicinal relevance depend on complex stereochemistry and substitution patterns. This team will build on their discovery of a cascade reaction for synthesising highly stereospecific indolene derivatives. They will target reagents and reaction pathways for creating heterocyclic molecules which are difficult to access. They will synthesise and characterise homo- and hetero-bimetallic complexes to develop cyclic molecules and scaffolds relevant in drug discovery. New molecules and reaction pathways will be relevant for biological and medicinal chemistry, and drug discovery programmes.

Funded Activity Details

Start Date: 02-2017

End Date: 12-2020

Funding Scheme: Discovery Projects

Funding Amount: $532,000.00

Funder: Australian Research Council