Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP210101755
Funding Status
Active
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Funded Activity Summary
Identification of Biological pathways regulated by circular RNAs. Circular RNAs (circRNAs) are a, recently discovered molecule. circRNAs are highly abundant and expressed in a tissue and disease specific manner. Yet, currently the understanding of how circRNAs regulate biological processes is very poor. This project aims to use pooled shRNA libraries to screen a large panel of cell lines and systematically identify cellular activities that are regulated by circRNAs. The expected outcome of this study will be a catalogue of functionally active circRNAs. Over the past decades, the wealth of knowledge on the function of linear mRNAs has had a significant impact on medicine and agriculture. Similarly understanding how circRNAs regulate cellular activities may have an analogous impact on humans.Funded Activity Details
Start Date: 03-2021
End Date: 02-2024
Funding Scheme: Discovery Projects
Funding Amount: $504,850.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Genome Structure and Regulation | Genomics | Cell Development, Proliferation and Death | Genetics
ANZSRC Socio-Economic Objective (SEO)
Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified |
