Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP210101317
Funding Status
Active
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Funded Activity Summary
Eradicating bacterial biofilms with nitroxide-antimicrobial hybrids. This project aims to develop new antimicrobials to address the rise of drug-resistant infections and resilient bacterial communities called biofilms. We aim to break new ground in our fundamental knowledge of antimicrobial mechanisms and exploit this understanding by fusing cellular/molecular microbiology and synthetic chemistry approaches. We seek to gain an in-depth understanding of how nitroxides induce bacterial biofilm dispersal, which is critical for the discovery of anti-biofilm molecules that do not fail due to resistance development. These breakthroughs should induce a step-change in our ability to reduce the occurrence of biofilm-related infection in fields ranging from medical and veterinary to biotechnology and agriculture.Funded Activity Details
Start Date: 12-2021
End Date: 11-2025
Funding Scheme: Discovery Projects
Funding Amount: $458,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Organic Chemistry | Free Radical Chemistry | Organic Chemical Synthesis | Bacteriology
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |
