ARC Future Fellowships - Grant ID: FT130101004

Funding Activity

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Funded Activity Summary

Molecular hallmarks of androgen receptor targeting in prostate cancer. There is a critical need in oncology drug development for better biomarkers of response to prostate cancer therapies, clinically to assist with treatment decision making, and pre-clinically to facilitate translation of emerging agents into clinical practice. Using a unique explant culture model, this project will identify protein and lipid markers that can be used to accurately and reliably assess response to androgen receptor (AR)-targeting therapies in human prostate tumours. The identification and functional assessment of these biomarkers will identify those that can be used as surrogate endpoints in clinical trials, facilitate earlier approval of investigational agents and lead to improved options for therapeutic management of prostate cancer.

Funded Activity Details

Start Date: 03-2014

End Date: 12-2018

Funding Scheme: ARC Future Fellowships

Funding Amount: $841,240.00

Funder: Australian Research Council