Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0880571
Funding Status
Closed
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Funded Activity Summary
Assessing the physiological roles of ubiquitination in regulating neuronal ion channels, receptors and transporters. Significant alterations in the activity neuronal transporters and receptors occur during tissue injury and regeneration as well as in many neurodegenerative disease states. Modulation of the pathways that control these transporters is an emerging therapeutic target, however, the molecular basis of these control mechanisms remain poorly understood. The outcome of this project will be a thorough characterisation of a novel regulatory paradigm in neurons that is likely to be crucial for neuronal development and regeneration, and will potentially provide novel therapeutic targets for various neuronal diseases.Funded Activity Details
Start Date: 2009
End Date: 12-2011
Funding Scheme: Discovery Projects
Funding Amount: $540,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Cellular Nervous System | Cell Physiology | Biochemistry and Cell Biology | Membrane Biology
